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BDNF — PARP1

Text-mined interactions from Literome

Hwang et al., J Neurochem 2002 : AEBSF or N-nitro-l-arginine ( NNA ) reduced BDNF mediated PARP activation
Wang et al., J Biol Chem 2006 : Here, we report that BDNF induces a sustained activation of ERK5 in rat cortical neurons and activates Rap1 , a small GTPase, as well as MEKK2, a MEK5 kinase ... Our data indicate that activation of Rap1 or MEKK2 is sufficient to stimulate ERK5, whereas inhibition of either Rap1 or MEKK2 attenuates BDNF activation of ERK5 ... Furthermore, BDNF stimulation of MEKK2 is regulated by Rap1