Nath et al., Proc Natl Acad Sci U S A 2003
(Colonic Neoplasms) :
Thus, NO-ASA inhibits Beta-catenin mediated TCF activity by preventing the formation of the Beta-catenin/TCF-4 complex
Yoo et al., Mol Pharmacol 2007
(Prostatic Neoplasms) :
Data from electrophoretic mobility shift assay and chromatin immunoprecipitation analyses revealed that ASA inhibited the transcription factor E2F-1 binding activity to the survivin promoter region, which is known to regulate survivin gene transcription