Gene interactions and pathways from curated databases and text-mining

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MDM2 — TREX1

Pathways - manually collected, often from reviews:

  • BioCarta atm signaling pathway: ATR/ATRIP/ATM complex (ATR-TREX1-ATM) → MDM2 (modification, activates)
  • BioCarta atm signaling pathway: ATR/ATRIP/ATM complex (ATR-TREX1-ATM) → p53/MDM2 complex (TP53-MDM2) (modification, activates)