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ATF2 — CREB1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Schinelli et al., J Neurosci 2001
:
By using selective protein kinase inhibitors and expression of dominant negative Rap1 protein, we also found that the Rap1/PKC/ERK dependent pathway
induces the phosphorylation of
activating transcription factor-1 , CREB, and Elk-1, whereas the p38MAPK dependent pathway only causes
CREB phosphorylation
Chang et al., Cell Signal 2003
(Brain Neoplasms) :
Conclusively, we present that both the disturbances of mitochondrial calcium homeostasis and reactive oxygen intermediates are essential for rapid transactivation of grp78, and this pathway is separate from protein kinase A (PKA) dependent
CREB activation or p38 mitogen activated protein kinase ( p38 ( MAPK ) ) -dependent
ATF-2 activation and signalling
Zhou et al., J Biochem Mol Biol 2007
:
The data from our experiments indicate that CREB1 overexpression inhibits SREBP-1c transcription, and that this action is antagonized by
CREB2 , a competitive
inhibitor of
CREB1
Samten et al., J Immunol 2008
:
Additionally,
ATF-2 controls expression of
CREB and c-Jun during T cell activation