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BCL2 — CDH1

Text-mined interactions from Literome

Sasaki et al., Int J Cancer 2000 (Neoplasm Invasiveness) : Therefore, E-cadherin may negatively regulate Bcl-2 expression by altering the availability of nuclear beta-catenin ... Loss of E-cadherin in invasive tumor cells may lead to increased Bcl-2 expression and resistance to chemotherapeutic drugs
Li et al., J Cell Sci 2003 : Overexpression of Bcl-2 in estrogen receptor positive MCF-7 mammary carcinoma cells led to decreased cell surface E-cadherin and the disruption of junctional complexes concurrent with intracellular redistribution of their components
Du et al., PLoS Biol 2007 (Adenoma, Islet Cell...) : Although no changes were observed in rates of proliferation or apoptosis, Bcl-xL altered cell morphology, remodeled the actin cytoskeleton, and down-regulated cadherin 1 ; it also induced cell migration and invasion, as evaluated using two-chamber transwell assays