Gene interactions and pathways from curated databases and text-mining

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AVP — PRKACB

Text-mined interactions from Literome

Wong et al., Metabolism 2003 : To examine the role of PKA in mediating an increase in AVP V2 mRNA expression, we incubated IMCD with 10 ( -7 ) and 10 ( -11 ) M of angiotensin II in the presence of a specific protein kinase A (PKA) inhibitor, Rp diasteroisomer of adenosine 3'-5'-cylic monophosphothionate ( Rp-cAMPS )
Umenishi et al., Biochim Biophys Acta 2006 : PKA activity was stimulated by AVP but PKA inhibitors did not block the upregulation of AQP2 expression
Stefan et al., J Am Soc Nephrol 2007 : In primary cultured principal cells, AVP causes focal activation of PKA
Hu et al., J Endocrinol 1992 (Second Messenger Systems) : These data provide direct evidence for a role for both PKC- and PKA mediated mechanisms in the regulation of CRF, AVP and oxytocin release and for differential effects of both glucocorticoids and mineralocorticoids on PKA- and PKC stimulated responses
Wong et al., J Clin Invest 1995 : When compared with basal MAPK activity of 26.4 +/- 6.6 pmol/mg/min in controls, basal MAPK activity varied widely in Ras transfected clones from 29.0 +/- 6.6 to 96.6 +/- 13.4 pmol/mg/min. Clones that functionally expressed activated Ras displayed complete abolition of AVP stimulated PKA activity, whereas those that failed to express elevated basal MAPK activity showed intact AVP stimulated PKA ... The correlation between expression of high basal MAPK activity and inhibition of AVP induced PKA yielded a correlation coefficient of -0.92 ( P = 0.009 ) ... The Raf clones showed no impairment of AVP stimulated PKA activity ... We conclude that expression of activated Ras is inhibitory of AVP induced PKA activation in the M-1 cortical collecting duct cell line at a site proximal to G alpha s protein
Prat et al., Am J Physiol 1993 : The cAMP dependent protein kinase A (PKA) in the presence of ATP induced and/or enhanced Na+ channel activity in excised inside-out patches with a change in average apparent channel number and percent open probability similar to those observed with either AVP or cAMP analogues in intact cells