◀ Back to BCL2
BCL2 — TXN
Text-mined interactions from Literome
Andoh et al., J Biol Chem 2003
:
The activated PKG is required to protect cells from lipid peroxidation and apoptosis, to inhibit caspase-9 and caspase-3 activation, and to elevate the levels of Trx peroxidase-1 and
Trx , which subsequently
induces the expression of
Bcl-2
Andoh et al., Mol Pharmacol 2005
:
We have observed that
thioredoxin (Trx) mediates the induction of mitochondrial manganese superoxide dismutase ( MnSOD ) and
Bcl-2 during preconditioning induced hormesis ...
Trx ( 1 microM ) consistently
increased the expression of mitochondrial proteins MnSOD and
Bcl-2 , supporting cell survival ( Andoh et al., 2002 )
Wang et al., J Biol Chem 2006
:
The down-regulation of
Trx2 expression
caused a decrease in the protein level of
Bcl-xL on day 3, whereas the protein level of Bcl-2 did not change until day 4, and the mRNA level of Bcl-xL was unchanged