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IL2 — LAT
Text-mined interactions from Literome
Kim et al., Biochem Biophys Res Commun 2009
:
Hph-1-ZAP-70-Y319F inhibited the phosphorylation of ZAP-70-Tyr319,
LAT-Tyr191 , and p44/42 MAPK
induced by TcR stimulation, NFAT- and AP-1 mediated gene transcription, and the induction of CD69 expression and
IL-2 secretion
Börner et al., J Biol Chem 2009
(Multiple Sclerosis) :
In this way the cannabinoids inhibited the T cell receptor triggered signaling, i.e. the activation of the zeta-chain associated protein kinase of 70 kDa, the
linker for activation of T cells , MAPK, the
induction of
interleukin-2 , and T cell proliferation
Chuck et al., J Immunol 2010
(Lymphoproliferative Disorders) :
Analysis of LATY136F T cells indicated that the interaction between
LAT and PLC-gamma1
plays an important role in TCR mediated signaling, proliferation, and
IL-2 production