Gene interactions and pathways from curated databases and text-mining

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CD79A — NOS1

Text-mined interactions from Literome

Sales et al., Int J Mol Med 1999 (HIV Infections) : On the one hand PKC activation by HIV+-IgA induces NOS inhibition and as a consequence, low amounts of NO that could improve local immunosuppression in the intestine ; on the other hand HIV+-IgA stimulates cGMP production which could potentiate ileal motility and loss of water/electrolytes involved in intestinal damage in AIDS
Budec et al., Alcohol Alcohol 2013 : Neuronal nitric oxide synthase mediates the effect of ethanol on IgA ... Taken together, these results extended our previous findings suggesting that nNOS mediates the acute effect of ethanol on IgA and supported an immunomodulatory role of this enzyme isoform