Gene interactions and pathways from curated databases and text-mining

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CD80 — IL6

Text-mined interactions from Literome

Fournier et al., Clin Immunol 2002 (Acquired Immunodeficiency Syndrome) : Ex vivo secreting peripheral B cells had probably gone beyond the CD40/CD40 ligand interaction ; then following CD28/CD80 and CD27/CD27 ligand ( CD70 ) interactions in the presence of IL-6 , they achieved in vitro their differentiation into plasma cells
Blanchet et al., Am J Respir Crit Care Med 2004 (Alveolitis, Extrinsic Allergic) : To test the effect of nicotine on alveolar macrophages, AMJ2-C11 cells were treated with nicotine and stimulated with lipopolysaccharide or Saccharopolyspora rectivirgula, a causative agent of HP. Nicotine reduced tumor necrosis factor release and tumor necrosis factor, interleukin-10 , and IFN-gamma mRNA expression after stimulation and decreased CD80 expression by 55 % in lipopolysaccharide stimulated cells and by 41 % in S. rectivirgula stimulated cells
Herrmann et al., Infect Immun 2006 (Encephalomyelitis, Autoimmune, Experimental...) : In contrast, the serum levels of tumor necrosis factor alpha and interleukin-6 and spinal interleukin-6 levels were elevated, and the expression of major histocompatibility complex class II molecules, CD80 , and CD86 on splenic dendritic cells were enhanced early after infection