UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to CCND1

CCND1 — CD44

Pathways - manually collected, often from reviews:

WikiPathways Wnt Signaling Pathway and Pluripotency: EP300 → Complex of 11 proteins (activation)
WikiPathways Wnt Signaling Pathway and Pluripotency: ZBTB33 → Complex of 11 proteins (mim-inhibition)

Text-mined interactions from Literome

Kothapalli et al., J Cell Biol 2007 : Analysis of arteries from wild-type and CD44-null mice showed that the effects of HMW-HA/CD44 on cyclin D1 and Skp2 gene expression are detected in vivo and are associated with altered SMC proliferation after vascular injury
Kothapalli et al., J Biol Chem 2008 : We now report that cyclin D1 is the primary target of LMW-HA in human vascular smooth muscle cells, as it is for HMW-HA, and that the opposing cell cycle effects of these CD44 ligands result from differential regulation of signaling pathways to cyclin D1