Gene interactions and pathways from curated databases and text-mining

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EGR1 — FOS

Text-mined interactions from Literome

Fujisaki et al., Neuroscience 2004 : In the pretraining lesioned rats that were trained for auditory conditioning, the number of c-Fos and Egr-1 decreased in the infralimbic cortex ( IL ) and the number of Egr-1 increased in the basomedial amygdaloid nucleus ( BM ) ... In the pretraining AHi lesioned rats that were trained for contextual conditioning, the number of c-Fos increased in the lateral periaqueductal gray ( LPAG ) and the number of Egr-1 increased in the BM
Sabuda-Widemann et al., Nephrol Dial Transplant 2009 : MPA was tested on the expression of platelet derived growth factor-B ( PDGF-B ) and its receptor beta ( PDGFR-beta ), the immediate early gene ( IEG ) c-fos and the early growth response gene-1 (Egr-1) , and AP-1 activation
Tarcic et al., FASEB J 2012 : In addition to strong activation of ERK by EGF, and AKT by serum, early transcription remarkably differed : while EGF induced early growth response-1 (EGR1) , and this was required for migration, serum induced c-Fos and FosB to enhance proliferation