Gene interactions and pathways from curated databases and text-mining

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IFNG — KLK3

Text-mined interactions from Literome

Okamoto et al., J Immunother 2000 (Adenocarcinoma...) : An interferon-gamma (IFN-gamma) inducing molecule ( OK-PSA ) has been purified from OK-432 by an affinity chromatographic technique performed on cyanogen bromide activated Sepharose 4B-bound TS-2 monoclonal antibody, which neutralizes IFN-gamma inducing activity of OK-432 ... Significantly less OK-PSA encapsulated into liposomes ( Lipo-OK-PSA ) than OK-PSA alone ( 1/100 or less of OK-PSA alone ) was required to induce IFN-gamma , tumor necrosis factor-alpha (TNF-alpha), TNF-beta, interleukin-1 beta (IL-1 beta), natural killer, and lymphokine activated killer activities by human peripheral blood mononuclear cells and mouse spleen cells
Okamoto et al., J Natl Cancer Inst 2003 (Head and Neck Neoplasms) : Although both OK-432 and OK-PSA induced IFN-gamma expression from PBMCs in vitro, expression of TLR4 and MD-2 was associated only with IFN-gamma expression induced by OK-PSA ( P < .001 )
Harada et al., J Immunother 2005 (Prostatic Neoplasms) : Both CD4+ T cells produced interferon-gamma in response to naturally processed PSA secreted from prostate cancer cells, whereas their reactivity to the administered PSA248-257 peptide was undetectable or negligible
Makino et al., J Dairy Sci 2006 : Stimulation of mouse splenocytes by H-APS significantly increased interferon-gamma production, and, moreover, orally administered H-APS augmented natural killer cell activity
Ohta et al., J Agric Food Chem 2007 (Orthomyxoviridae Infections) : Furthermore, APS increased TNF-alpha and IFN-gamma levels in mice when compared with those of untreated mice
Kouiavskaia et al., J Immunother 2009 (Neoplasm Recurrence, Local...) : No IFN-gamma response to PSA : 154-163 ( 155L ) was detected in unfractioned PBMC in any patient either before or after vaccination ... Three of 5 patients demonstrated strong IFN-gamma responses to PSA : 154-163 ( 155L ) and native PSA : 154-163 peptides in CD8 T-cell cultures derived from postvaccination PBMC