Gene interactions and pathways from curated databases and text-mining

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IRF6 — STS

Text-mined interactions from Literome

Mamchak et al., Immunol Cell Biol 2000 : Through the use of haptenated Ficoll, it was possible to show that the generation of LPS induced antitrinitrophenol ASC could be inhibited by antigen presented on an inert substrate
Mamchak et al., Immunol Cell Biol 2000 : Cyclosporine A did not block the inhibitory effects of goat anti-IgM ( galphaIgM ) on development of ASC induced by LPS and therefore was unsuitable for testing between the two models
Shiohara et al., Biochem Biophys Res Commun 2002 (Inflammation) : ASC expression was transiently up-regulated by IL-1alpha, IL-1beta, IFN-alpha, IFN-gamma, TNFalpha, and LPS
Hindle et al., Infect Immun 2002 (Salmonella Infections...) : Six of nine volunteers elicited anti-serovar Typhi lipopolysaccharide (LPS) immunoglobulin A (IgA) antibody secreting cell (ASC) responses , with three of three vaccinees receiving 10 ( 8 ) and two of three receiving 10 ( 9 ) CFU which elicited high-titer LPS-specific serum IgG
Li et al., J Infect 1994 : Local mucosal immune responses and antibody secreting cell (ASC) responses to S. flexneri lipopolysaccharide (LPS) and invasion plasmid coded antigens ( Ipa ) were elicited in the children in a dose dependent manner
Losonsky et al., Infect Immun 1993 (Cholera) : We evaluated the ASC response to cholera toxin ( CT ) and Inaba lipopolysaccharide (LPS) in 26 North American volunteers following immunization with a single oral dose of live attenuated Vibrio cholerae O1 vaccine strain CVD 103-HgR and again upon homologous wild-type challenge with V. cholerae classical Inaba 569B ... The CT and LPS ASC responses of volunteers following vaccination ( 83 and 55 %, respectively ) were similar in magnitude and frequency to those of unvaccinated controls following wild-type challenge ( 80 and 60 %, respectively [ 0.1 < or = P < or = 0.9 ] ) ... The responses were primarily immunoglobulin A. Vaccinated volunteers challenged within 30 days of vaccination had reduced or nondetectable CT and LPS ASC responses ... Challenge at 6 months resulted in a heightened ASC response to LPS , confirming the existence of mucosal memory
Li et al., Vaccine 1993 (Dysentery, Bacillary) : flexneri LPS and anti-Ipa faecal sIgA titres were significantly higher ( p < 0.05 to p < 0.01 ) than after primary vaccination ; ( iii ) the anti-LPS and anti-Ipa ASC responses were significantly lower ( p < 0.05 ) and of shorter duration than after primary vaccination, and ( iv ) the serum anti-LPS and anti-Ipa responses were significantly elevated ( p < 0.05 ) and similar to those seen after primary vaccination