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INS — PPP3R1

Text-mined interactions from Literome

Lester et al., Endocrinology 2001 : Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation ... Transient inhibition of PP-2B , using the immunosuppressant FK506, increased forskolin stimulated insulin secretion by 2.5-fold +/- 0.3 ( n = 6 ) in rat islets and RINm5F cells
Donelan et al., J Biol Chem 2002 (Insulinoma...) : They also implicate a novel regulatory role for PP2B/calcineurin in the control of insulin secretion downstream of a rise in [ Ca2+ ] i
Duan et al., Proc Natl Acad Sci U S A 2010 (Calcium Signaling...) : Calcineurin controls insulin gene expression by ERK1/2 dependent and -independent mechanisms