UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to ITGAV

IBSP — ITGAV

Pathways - manually collected, often from reviews:

KEGG Focal adhesion: CHAD/COL11A1/COL11A2/COL1A1/COL1A2/COL2A1/COL3A1/COL4A1/COL4A2/COL4A4/COL4A5/COL4A6/COL5A1/COL5A2/COL5A3/COL6A1/COL6A2/COL6A3/COL6A6/COMP/FN1/IBSP/LAMA1/LAMA2/LAMA3/LAMA4/LAMA5/LAMB1/LAMB2/LAMB3/LAMB4/LAMC1/LAMC2/LAMC3/RELN/SPP1/THBS1/THBS2/THBS3/THBS4/TNC/TNN/TNR/TNXB/VTN/VWF → Complex of 21 proteins (protein-protein, activation)
KEGG ECM-receptor interaction: IBSP → Complex of ITGAV-ITGB3 (protein-protein, activation)
KEGG ECM-receptor interaction: IBSP → Complex of ITGAV-ITGB5 (protein-protein, activation)
NCI Pathway Database Beta3 integrin cell surface interactions: alphav/beta3 Integrin/Bone sialoprotein 2 complex (IBSP-ITGAV-ITGB3) → alphav/beta3 Integrin complex (ITGAV-ITGB3) (modification, collaborate)
Byzova et al., Exp Cell Res 2000 *, Helfrich et al., J Bone Miner Res 1992 *, Oldberg et al., J Biol Chem 1988 *
Evidence: physical interaction
NCI Pathway Database Beta3 integrin cell surface interactions: alphav/beta3 Integrin/Bone sialoprotein 2 complex (IBSP-ITGAV-ITGB3) → Bone sialoprotein 2 (IBSP) (modification, collaborate)
Byzova et al., Exp Cell Res 2000 *, Helfrich et al., J Bone Miner Res 1992 *, Oldberg et al., J Biol Chem 1988 *
Evidence: physical interaction
NCI Pathway Database Beta3 integrin cell surface interactions: alphav/beta3 Integrin complex (ITGAV-ITGB3) → Bone sialoprotein 2 (IBSP) (modification, collaborate)
Byzova et al., Exp Cell Res 2000 *, Helfrich et al., J Bone Miner Res 1992 *, Oldberg et al., J Biol Chem 1988 *
Evidence: physical interaction
Reactome Reaction: ITGAV → IBSP (indirect_complex) Byzova et al., Exp Cell Res 2000 *
Reactome Reaction: ITGAV → IBSP (reaction) Byzova et al., Exp Cell Res 2000 *
WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: COL4A2/CHAD/TNR/COL11A2/LAMB3/COMP/COL1A2/FN1/THBS2/COL5A1/RELN/LAMC3/LAMC2/LAMB1/COL4A6/TNC/COL5A2/LAMA4/COL4A1/LAMA3/LAMC1/LAMB2/THBS4/COL2A1/THBS3/LAMA5/IBSP/COL6A2/VWF/TNXB/TNN/SPP1/LAMA2/COL3A1/LAMA1/VTN/THBS1/COL1A1/COL11A1/COL5A3/COL4A4 → ITGA5/ITGAE/ITGAX/ITGAD/ITGA7/ITGA2B/ITGA9/ITGA2/PELO/ITGA3/ITGA8/ITGA10/ITGAV/ITGA6/ITGAL/ITGA4/ITGA11 (activation)