Gene interactions and pathways from curated databases and text-mining

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NOX3 — PRKCA

Text-mined interactions from Literome

Fontayne et al., Biochemistry 2002 : Taken together, these results suggest that PKC alpha , beta II, delta, and zeta expressed in human neutrophils can individually phosphorylate p47(phox) and induce both its translocation and NADPH oxidase activation
Abdala-Valencia et al., J Immunol 2006 : The anti-VCAM-1 stimulated phosphorylation of PKCalpha ( Thr638 ) was blocked by scavenging of H ( 2 ) O ( 2 ) and by inhibition of NADPH oxidase
Thallas-Bonke et al., Diabetes 2008 (Diabetes Mellitus, Experimental...) : In the context of these and previous findings by our group, we conclude that activation of NADPH oxidase via phosphorylation of PKC-alpha is downstream of the AGE-receptor for AGE interaction in diabetic renal disease and may provide a novel therapeutic target for diabetic nephropathy
Hong et al., American journal of physiology. Renal physiology 2010 : We concluded that flow stimulates net O ( 2 ) ( - ) production in thick ascending limbs via PKC-alpha mediated activation of NADPH oxidase