Gene interactions and pathways from curated databases and text-mining

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CDKN1A — FGF1

Text-mined interactions from Literome

Kivinen et al., Cell Growth Differ 1999 : In contrast, FGF-2 regulation of p21 is largely independent of MEK and Ras
David et al., J Otolaryngol 2002 : PCNA, Bcl-2, p53, and p21 in noise exposed and non-noise exposed guinea pig cochleas are not affected by exogenous FGF-1
Bellosta et al., J Bone Miner Res 2003 : We studied the expression of several cell cycle regulatory molecules in response to fibroblast growth factor, and found that fibroblast growth factor strongly upregulates the expression of p21 ( WAF1/CIP1 ), a CDK inhibitor that has also been implicated in the regulation of apoptosis and cell differentiation
Bouleau et al., Oncogene 2005 (Disease Progression...) : In the presence of FGF1 , p53 was unable to transactivate bax, but no modification of p21 gene transactivation was observed
Johnson et al., Oncogene 1998 (Breast Neoplasms...) : FGF signaling activates STAT1 and p21 and inhibits the estrogen response and proliferation of MCF-7 cells