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Giorgi et al., Science 2010
(Calcium Signaling) :
Pml was essential for Akt- and PP2a dependent modulation of IP ( 3 ) R phosphorylation and in turn for IP ( 3 ) R-mediated Ca ( 2+ ) release from ER
Rokudai et al., Proc Natl Acad Sci U S A 2013
(Leukemia, Promyelocytic, Acute) :
As a result of PML mediated suppression of Akt , the increased PML-MOZ interaction enhances p21 expression and induces p53 dependent premature senescence upon forced PML expression