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IL6 — SAA4

Text-mined interactions from Literome

Nguyen et al., J Biol Chem 1999 : Treatment of primary rat hepatocytes or tranfected HepG2 cells with the alpha ( 1B ) -adrenergic receptor ( alpha ( 1B ) AR ) agonist phenylephrine ( PE ) significantly inhibited interleukin 6 (IL-6) induced STAT3 binding, tyrosine phosphorylation, and IL-6 induced serum amyloid A mRNA expression
Hayashi et al., Proc Natl Acad Sci U S A 2002 (Bone Resorption) : Not only did MDL-A markedly inhibit IL-6- and IL-11 induced osteoclastogenesis in vitro, but it also inhibited IL-6 stimulated serum amyloid A production and bone resorption in an experimental model of postmenopausal osteoporosis in vivo by a different mechanism from that of 17beta-estradiol
Gervois et al., J Biol Chem 2004 (Acute-Phase Reaction) : PPARalpha prevents the IL-6 induced expression of the positive APR genes fibrinogen-alpha, -beta, -gamma, haptoglobulin, and serum amyloid A and the IL-6 induced suppression of the negative APR gene, major urinary protein
Kuzuhara et al., Eur J Pharmacol 2006 (Liver Failure) : We examined whether the 22beta-methoxyolean-12-ene-3beta,24 ( 4beta ) -diol ( ME3738 ) -mediated selective induction of interleukin-6 increased alpha1-acid glycoprotein and serum amyloid A expression, and whether these proteins protected against liver injury in vitro and in vivo
Migita et al., J Rheumatol 2011 (Acute-Phase Reaction...) : By contrast IL-6 stimulation did not affect SAA4 mRNA expression, which is expressed constitutively in RA-FLS
Mackiewicz et al., Biochem J 1988 : Comparison of these findings with those in human hepatoma cell lines, in which interleukin-1 does not induce serum amyloid A synthesis, suggests that the effect of interleukin-1 on serum amyloid A synthesis may be indirect
Weinstein et al., J Trauma 1987 (Acute-Phase Reaction...) : The effect of interleukin-1 on mouse liver serum amyloid A mRNA levels was investigated
Moshage et al., Biochem Biophys Res Commun 1988 : The effect of interleukin-1 , interleukin-6 and its interrelationship on the synthesis of serum amyloid A and C-reactive protein in primary cultures of adult human hepatocytes ... These findings suggest that IL-6 plays a key role in the stimulation of synthesis of serum amyloid A and C-reactive protein by the human liver cells
Jiang et al., J Immunol 1995 : Induction of human serum amyloid A in Hep 3B cells by IL-6 and IL-1 beta involves both transcriptional and post-transcriptional mechanisms