Knop et al., EMBO J 2004
:
Rab3D and annexin A2 play a role in regulated secretion of vWF , but not tPA, from endothelial cells ... siRNA mediated downregulation of annexin A2/S100A10 and disruption of the complex by microinjection of peptide competitors result in a marked reduction in vWF but not tPA secretion, without affecting the appearance of WPbs
Brandherm et al., Blood 2013
:
Knockdown and specific rescue approaches reveal that a functional AnxA2-S100A10 complex is required for the forskolin induced, cAMP dependent release of VWF