Hu et al., Acta Pharmacol Sin 2008
(Calcium Signaling) :
Rg1 activated ERK/MAPK pathway by CaMKIIalpha, and the activation of CREB was not only dependent on ERK induced by Rg1 , which may provide an explanation for the effect of Rg1 on long-term potentiation
Lau et al., Br J Pharmacol 2009
(Breast Neoplasms...) :
Rg1 could induce MEK protein expression and the phosphorylation level of MEK and ERK significantly in a time- and dose dependent manner
Wu et al., Neuropharmacology 2012
:
Meantime, Rg1 also increases the basal level of ERK1/2 phosphorylation