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IL6 — IRAK1

Text-mined interactions from Literome

Jensen et al., J Biol Chem 2001 (Carcinoma, Hepatocellular...) : IRAK1b , a novel alternative splice variant of interleukin-1 receptor associated kinase ( IRAK ), mediates interleukin-1 signaling and has prolonged stability
Kim et al., J Biol Chem 2005 (Inflammation) : Importantly, endogenous mPLK/IRAK was activated in response to TNF-alpha or interleukin 1 treatment of primary adipose cells
Rao et al., Mol Cell Biol 2005 (Inflammation) : Overexpression of IRAK1c suppressed NF-kappaB activation and blocked IL-1beta induced IL-6 as well as lipopolysaccharide- and CpG induced tumor necrosis factor alpha production in multiple cellular systems
Song et al., Mol Immunol 2009 (Inflammation) : In contrast, an inhibitor of both IRAK-1 and IRAK-4 ( RO0884 ) reduced IL-1beta induced p38 MAP kinase, c-Jun N-terminal kinase activation, and IL-6 production in HUVEC
Eda et al., Cell Biol Int 2011 (Arthritis, Rheumatoid) : Interleukin-1ß induced interleukin-6 production in A549 cells is mediated by both phosphatidylinositol 3-kinase and interleukin-1 receptor associated kinase-4