Gene interactions and pathways from curated databases and text-mining

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HMOX1 — TCF24

Text-mined interactions from Literome

Bauer et al., Shock 2003 : Although activator protein-1 has been reported as the predominant redox-sensitive transcription factor inducing HO-1 expression in murine macrophages, nuclear factor kappaB seems to play a significant role in human mononuclear cells
Wijayanti et al., J Biol Chem 2005 (Inflammation) : Overexpression of the basic helix-loop-helix transcription factor USF2 and coactivator p300 enhanced the AEBSF dependent response of the HO-1 promoter
Harrison et al., FEBS J 2006 (Adenocarcinoma...) : Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells
Sun et al., International journal of biological sciences 2008 : The expression of HO-1 , iNOS ( Western blot ) and ICAM-1 ( cell ELISA ) proteins and activation of inflammation-relevant transcription factor , NF-kappaB ( EMSA ) were assessed
MacGarvey et al., Am J Respir Crit Care Med 2012 (Disease Models, Animal...) : HO-1/CO stimulated Nrf2 dependent gene expression and nuclear accumulation of nuclear respiratory factor-1, -2a ( Gabpa ), and peroxisome proliferator activated receptor gamma coactivator-1a ; increased mitochondrial transcription factor-A and citrate synthase protein levels ; and augmented mtDNA copy number