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CDC42 — STK11
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
CDC42
→
STK11
(increases, CDC42 Activity)
Evidence: LKB1 can also regulate the polarization of lung cancer cell lines in association with recruitment of the small GTPase, Cdc42, a known regulator of cell polarity (Zhang et al., 2008 and see Etienne-Manneville, 2008).
Text-mined interactions from Literome
Harden et al., Mol Cell Biol 1996
:
A Drosophila homolog of the Rac- and
Cdc42 activated
serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures
Wu et al., EMBO J 1997
:
Cdc2/Cdc13 activity is also indirectly
regulated by the approximately 70 kDa Nim1 ( Cdrl )
serine/threonine kinase , which promotes mitosis by inhibiting Wee1 via direct phosphorylation
Yablonski et al., EMBO J 1998
:
This
serine/threonine kinase is
activated by GTP bound Rac1 or
Cdc42