Gene interactions and pathways from curated databases and text-mining

◀ Back to STK11

CDC42 — STK11

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: CDC42 → STK11 (increases, CDC42 Activity)
    Evidence: LKB1 can also regulate the polarization of lung cancer cell lines in association with recruitment of the small GTPase, Cdc42, a known regulator of cell polarity (Zhang et al., 2008 and see Etienne-Manneville, 2008).

Text-mined interactions from Literome

Harden et al., Mol Cell Biol 1996 : A Drosophila homolog of the Rac- and Cdc42 activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures
Wu et al., EMBO J 1997 : Cdc2/Cdc13 activity is also indirectly regulated by the approximately 70 kDa Nim1 ( Cdrl ) serine/threonine kinase , which promotes mitosis by inhibiting Wee1 via direct phosphorylation
Yablonski et al., EMBO J 1998 : This serine/threonine kinase is activated by GTP bound Rac1 or Cdc42