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IL8 — TAB1
Text-mined interactions from Literome
Channavajhala et al., J Biol Chem 2003
(MAP Kinase Signaling System) :
Moreover, Cot induced interleukin-8 production in HeLa cells is almost completely inhibited by the concurrent expression of hKSR-2, whereas transforming growth factor beta activated kinase 1 ( TAK1 )
/TAK1 binding protein 1 (TAB1) induced
interleukin-8 production is not affected by hKSR-2 co-expression
Frobøse et al., Mol Endocrinol 2006
:
Suppressor of cytokine Signaling-3
inhibits interleukin-1 signaling by targeting the
TRAF-6/TAK1 complex
Thiefes et al., EMBO Rep 2006
:
YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and
interleukin-1-inducible activation of endogenous TAK1,
TAB1 and TAB2 ... YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and
interleukin-1-inducible activation of endogenous TAK1,
TAB1 and TAB2 ... YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and
interleukin-1-inducible activation of endogenous
TAK1 , TAB1 and TAB2
Zhou et al., World J Gastroenterol 2008
(Adenocarcinoma...) :
Viable LBG or LBG- ( s ) pretreatment attenuated the expression of TLR4,
inhibited the phosphorylation of
TAK1 and p38MAPK, prevented the activation of NF-kappaB, and consequently blocked
IL-8 production
Kim et al., PloS one 2009
(Colitis) :
Finally, we showed that
TAK1 is
essential for
interleukin 1- and bacterial components induced expression of cytoprotective factors such as interleukin 6 and cycloxygenase 2
Pera et al., Am J Physiol Lung Cell Mol Physiol 2012
(MAP Kinase Signaling System) :
In addition, inhibitors of
TAK1 and the NF-?B ( SC-514 ; 50 µM ) and ERK-1/2 ( U-0126 ; 3 µM ) signaling
inhibited the CSE induced
IL-8 release by ASM cells ... These data indicate that
TAK1 plays a major role in CSE induced ERK-1/2 and NF-?B signaling and in
IL-8 release by human ASM cells