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IL1A — MAP3K8

Text-mined interactions from Literome

Rodríguez et al., Cell Signal 2006 : This Src kinases inhibitor does not block the dissociation and subsequently degradation of Cot in response to IL-1 , indicating that other events besides Cot dissociation are required to activate Cot
Stafford et al., FEBS Lett 2006 : The protein kinase COT/Tpl2 is activated by interleukin-1 (IL-1) , TNFalpha and lipopolysaccharide, and its activation by these agonists involves the IkappaB kinase beta (IKKbeta) catalysed phosphorylation of the p105 regulatory subunit