Gene interactions and pathways from curated databases and text-mining

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IL17A — MYD88

Text-mined interactions from Literome

Chang et al., J Biol Chem 2006 (Inflammation...) : MyD88 and IRAK4, downstream signaling components of TIR, are not required for IL-17 signaling
Hot et al., Ann Rheum Dis 2011 (Arthritis, Rheumatoid) : IL-17A and, to a lesser extent, IL-17F induced TRAF6 but not MyD88
Keestra et al., Infect Immun 2011 (Colitis...) : Early MyD88 dependent induction of interleukin-17A expression during Salmonella colitis ... Furthermore, initial expression of IL-17A at 24 h after S. Typhimurium infection was dependent on MyD88 and the receptor for IL-1ß
Roark et al., Immunol Res 2013 : Their IL-17A response requires the toll-like receptor adapter protein MyD88 , and their activation is enhanced by IFN?, although aß T cells need not be present
Shenderov et al., J Immunol 2013 : We found that IL-17 secretion by CD4 ( + ) T cells following CFA immunization requires MyD88 and IL-1ß/IL-1R signaling ... Through measurement of Ag-specific responses after adoptive transfer of OTII cells, we confirmed that MyD88 dependent signaling controls Th17 differentiation rather than simply production of IL-17