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PIK3R1 — PLA2G1B
Text-mined interactions from Literome
Park et al., J Immunol 2003
:
Pretreatment with LY294002, a PI3K inhibitor, strongly suppressed group IIA
PLA(2) induced iNOS expression and
PI3K/Akt activation
Myou et al., J Immunol 2003
(MAP Kinase Signaling System) :
We find that
PI3K is
required for
gIV-PLA(2) activation and hydrolytic production of AA in activated eosinophils ... Our data suggest that this essential
PI3K independently
activates gIV-PLA(2) through a pathway that does not involve MAPK
Araki et al., Free Radic Biol Med 2005
:
PLA2 , COX, PKC, NADH dehydrogenase, and XO inhibitors
prevented the CA-induced ROS generation but not ERK 1/2,
PI 3 K , p38 MAPK, and MLCK inhibitors
Wang et al., Cardiovasc Res 2010
(Atherosclerosis) :
Inhibition of either
PI3K or p38 MAPK completely
blocked oxLDL induced
lp-PLA2 expression