◀ Back to PPP2R1A
IL6 — PPP2R1A
Text-mined interactions from Literome
Boudreau et al., J Biol Chem 2002
:
The
PP2A inhibitor okadaic acid induced P. aeruginosa-like responses in mast cells including increased PKCalpha phosphorylation, stimulated PKC activity, and
augmented IL-6 production, the last being blocked by the PKC inhibitor Ro 31-8220
Nizamutdinova et al., J Cell Physiol 2013
(Hyperglycemia) :
Moreover, ATRA and LGD1069 reversed the decreased
PP2A activity and
inhibited the activation of IKK/I?Ba and gene expression of MCP-1,
IL-6 , and TNF-a in the hearts of Zucker diabetic fatty rats
Choi et al., Immunol Lett 1998
:
In addition, co-transfection of protein phosphatase 2A (PP2A) antisense constructs further increased IL-6 induced IRF-1 promoter activity, suggesting that
PP2A is
involved in
IL-6 signaling ... In addition,
IL-6 directly
induced the
PP2A phosphorylation ... Furthermore,
IL-6 activated
PP2A activity simultaneously