Gene interactions and pathways from curated databases and text-mining

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GPX8 — NFKB1

Text-mined interactions from Literome

Zhou et al., Free Radic Biol Med 2001 : To test whether NF kappa B or AP-1 might be mediating the induction of GPx and CAT in muscle cells subjected to oxidative stress, we first characterized their activation by pro-oxidants ... In summary, our results suggest that NF kappa B and AP-1 are important mediators of redox-responsive gene expression in skeletal muscle, and that at least NF kappa B is actively involved in the upregulation of the GPx and CAT in response to oxidative stress
ViƱa et al., Biol Chem 2008 : Activation of NF-kappa B by estrogens subsequently activates the expression of Mn-SOD and GPx , but genistein is only capable of activating Mn-SOD expression
Kretz-Remy et al., J Cell Biol 1996 : Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression