Gene interactions and pathways from curated databases and text-mining

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AVP — IL2

Text-mined interactions from Literome

Raab et al., Clin Endocrinol (Oxf) 1999 (Kidney Neoplasms...) : We determined the interleukin-6, big-endothelin, endothelin-1, ACTH, cortisol and AVP responses to intravenously and subcutaneously administered interleukin-2 in 8 cancer patients in a randomized placebo controlled trial ... Interleukin-2 had no detectable effect on AVP , blood pressure or heart rate
Raber et al., J Neurosci 1994 : In the present study, we evaluated the effect of IL-2 on the in vitro release of AVP from the hypothalamus and amygdala ... IL-2 rapidly stimulates AVP release in both regions, in a calcium- and dose dependent manner ... Our results suggest that in addition to CRF, AVP may also mediate the IL-2 stimulation of ACTH secretion
Hillhouse et al., Brain Res 1994 : Interleukin-2 stimulates the secretion of arginine vasopressin but not corticotropin releasing hormone from rat hypothalamic cells in vitro ... In this study IL-2 caused a dose dependent stimulation of AVP secretion from both the intact rat hypothalamus in vitro and hypothalamic cell cultures
Raber et al., Neuroscience 1996 : When the release of arginine vasopressin induced by interferon-alpha, interleukin-2, acetylcholine and norepinephrine was probed with inhibitors of guanylate cyclase, the interactions exhibited regional selectivity : neither the interleukin-2 induced arginine vasopressin release from hypothalamus, nor the norepinephrine induced release of arginine vasopressin from either amygdala or hypothalamus was affected by guanylate cyclase inhibitors, but all other arginine vasopressin releasers were blocked
Raber et al., Brain research. Brain research reviews 1998 (Disease Models, Animal...) : IL1beta, IL2 , IL6, and IFNalpha will each enhance the release of AVP in slices of rat hypothalamus and amygdala