Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of JAK3-VIL1
→
IL2
(increases)
Kumar et al., J Biol Chem 2007* Evidence: In these cells Jak3 interacted with the intestinal and renal epithelial cell-specific cytoskeletal protein villin in an IL-2-dependent manner. Inhibition of Jak3 activation resulted in loss of tyrosine phosphorylation of villin and a significant decrease in wound repair of the intestinal epithelial cells.