Gene interactions and pathways from curated databases and text-mining

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MMP1 — RAF1

Text-mined interactions from Literome

Westermarck et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : The activation of the extracellular signal regulated kinase 1 ( ERK1 ) /ERK2 ( designated ERK1,2 ) pathway by oncogenic Ras, constitutively active Raf-1 , or phorbol ester resulted in potent stimulation of MMP-1 promoter activity and mRNA expression
Pap et al., Arthritis Rheum 2004 (Arthritis, Rheumatoid) : Immunohistochemistry was used to study the effects of DN c-Raf-1 on phosphorylated c-Jun and matrix metalloproteinase 1 (MMP-1) in RASFs implanted into SCID mice
Izbicka et al., Anticancer Res 2005 (Breast Neoplasms...) : R115777 +/- paclitaxel inhibited HDJ-2 farnesylation, up-regulated RhoB, transiently lowered ( P ) ERK/ERK and ( P ) Akt/Akt, reduced Raf-1 and MEK and inhibited secretion of VEGF and MMP-1