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APOE — EPHB2
Text-mined interactions from Literome
Hoe et al., J Neurochem 2005
:
ERK1/2 activation by
apoE was blocked by an inhibitor of the low-density lipoprotein receptor family, the specific NMDA glutamate receptor antagonist MK 801 and other calcium channel blockers
Liu et al., Journal of neuroinflammation 2011
(Inflammation) :
Inhibitors of MAPK-p38,
ERK , and JNK
inhibited ApoE induction by all these agents except glutamate, which was sensitive only to inhibitors of ERK and JNK
Kim et al., Exp Cell Res 2013
:
While ApoE did not affect the activation of
ERK , JNK, and p38 MAPK signaling pathways by RANKL, the phosphorylation of p65 trans-activation domain on serine 536 and transcription activity of NF-?B were
reduced by
ApoE overexpression