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CDK2 — EGF

Text-mined interactions from Literome

Heo et al., Am J Physiol Cell Physiol 2006 (MAP Kinase Signaling System) : Finally, inhibition of EGFR tyrosine kinase, PKC, Ca2+ channels, or p44/42 MAPKs attenuated EGF stimulated cyclin D1, cyclin E, cyclin dependent kinase (CDK)2 , and CDK4, respectively
Lee et al., J Cell Biochem 2006 : In addition, PD 98059 ( a MEK inhibitor ), SB 203580 ( a p38 MAPK inhibitor ), and SP 600125 ( a JNK inhibitor ) blocked the EGF induced stimulation of [ 3H ] -thymidine incorporation and CDK-2/4 expression ... Moreover, EGF increased the CDK-2 , CDK-4, cyclin D1, and cyclin E expression levels but decreased the p21 and p27 expression levels
Flinder et al., J Cell Physiol 2013 : All three sites were central for EGF induced ERK-activity and Cdk2 expression