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ARG1 — TGFB1
Text-mined interactions from Literome
Djeraba et al., Vet Microbiol 2002
(Disease Susceptibility...) :
Differential expression of NO synthase and
arginase was modulated in chicken macrophages, with IFN-gamma and LPS being strong inducers of both, depending on the type of macrophage, and
TGF-beta 1 and PGE ( 2 )
stimulating only arginase activity
Witte et al., J Surg Res 2002
:
The
effect of
transforming growth factor beta1 ( TGF-beta1 ), interleukin-4 (IL-4), lipopolysaccharide, and wound fluid on
arginase activity was also investigated
Jost et al., FASEB J 2003
:
Divergent
effects of GM-CSF and
TGFbeta1 on bone marrow derived macrophage
arginase-1 activity, MCP-1 expression, and matrix metalloproteinase-12 : a potential role during arteriogenesis
Ito et al., Kidney Int 2005
(Fibrosis...) :
ARG did not
affect renal NOS expression and tissue
TGF-beta1 levels
Kitowska et al., Am J Physiol Lung Cell Mol Physiol 2008
(Pulmonary Fibrosis) :
TGF-beta1 induced upregulation of
arginase-1 suggests an interplay between profibrotic agents and l-arginine metabolism during the course of lung fibrosis in the mouse, whereas species-specific regulatory mechanisms may account for the differences observed in mouse and human
Mabalirajan et al., Am J Physiol Lung Cell Mol Physiol 2009
(Asthma...) :
Increased Th ( 2 ) cytokines such as IL-4 and IL-13
induce arginase either directly or indirectly through
transforming growth factor-beta(1) ( TGF-beta(1) ) and lead to subepithelial fibrosis, which is a crucial component of airway remodeling
Stempin et al., J Biomed Biotechnol 2010
(Parasitic Diseases) :
Arginase-1 can also be
induced by IL-10 and
transforming growth factor-beta ( TGF-beta ) or even directly by parasites or parasite components