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CCL2 — IL2

Text-mined interactions from Literome

Murao et al., FEBS Lett 1999 : In human vascular endothelial cells, interleukin-1beta and tumor necrosis factor-alpha induced endogenous monocyte chemoattractant protein-1 protein secretion, mRNA expression and promoter activity
Ishikawa et al., J Am Soc Nephrol 1999 : Bioflavonoid quercetin inhibits interleukin-1 induced transcriptional expression of monocyte chemoattractant protein-1 in glomerular cells via suppression of nuclear factor-kappaB
Akoum et al., J Clin Endocrinol Metab 2000 (Endometriosis) : Estradiol amplifies interleukin-1 induced monocyte chemotactic protein-1 expression by ectopic endometrial cells of women with endometriosis ... In the present study we report that estradiol ( E2 ) enhances endometriotic cell responsiveness to the proinflammatory cytokine interleukin-1beta by up-regulating interleukin-1 induced monocyte chemotactic protein-1 (MCP-1) expression at the level of both protein secretion and messenger ribonucleic acid ( mRNA ) synthesis, whereas progesterone had no significant effects
Corrigall et al., J Immunol 2001 (Arthritis, Rheumatoid) : The functional capability of these receptors was confirmed by the production of monocyte chemoattractant protein-1 ( MCP-1 ) in direct response to stimulation by IL-2 , which could be inhibited by neutralizing anti-CD122 mAb ... The addition of neutralizing anti-CD122 mAb to FLS cultures partially, but significantly, reduced the IL-2 induced MCP-1 secretion, but did not effect either the spontaneous or IL-1 beta induced secretion of MCP-1
Momoi et al., Chest 2001 (Adenocarcinoma...) : In A549 cells, interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha induced endogenous MCP-1 protein secretion and messenger RNA expression
Ozawa et al., J Leukoc Biol 2003 (Periodontitis) : IL-2Rbeta, and -gamma expressed on HGF were functionally active, as addition of neutralizing anti-IL-2Rbeta and -gamma antibodies caused inhibition of the IL-2 induced production of monocyte chemoattractant protein-1 ( MCP-1 ), and addition of IL-2 induced phosphorylation of Janus tyrosine kinase 3, which is critical in signaling through IL-2Rgamma in HGF ... The IL-2 induced MCP-1 production was significantly inhibited by pretreatment with neutralizing antibody to IL-15
Ozawa et al., J Immunol 2004 (Periodontitis) : We recently reported that anti-IL-15 neutralizing mAb has been shown to inhibit production of MCP-1 in response to IL-2 from normal human gingival fibroblasts (HGF), the major constituent of gingival tissue ... Exogenous IL-2 and IL-15 induced production of MCP-1 but not IL-8 in normal HGF, and induced the production of both chemokines in inflamed HGF ... Pretreatment with anti-IL-15 neutralizing mAb for 24 h completely inhibited the production of MCP-1 induced by IL-2 and IL-15 and IL-2 induced phosphorylation of Jak 1 and 3 in HGF
Elhofy et al., J Leukoc Biol 2005 (Encephalomyelitis, Autoimmune, Experimental) : Overexpression of CCL2 in the CNS resulted in decreased interleukin-12 receptor expression by antigen-specific T cells
Burel et al., Nucleic acid therapeutics 2013 : In mice, the alterations at 70 mg/kg/week included spleen weight increase up to 1.4-fold relative to control, increases in alanine aminotransferase and aspartate aminotransferase up to 1.8-fold over control, interleukin-10 increases up to 3.7-fold, and monocyte chemoattractant protein-1 increase up to 1.9-fold over control
Goppelt-Struebe et al., FEBS Lett 1995 : Synergistic induction of monocyte chemoattractant protein-1 ( MCP-1 ) by platelet derived growth factor and interleukin-1
Hayashi et al., J Neuroimmunol 1995 : Lipopolysaccharide (LPS), interleukin (IL)-1 beta and tumor necrosis factor (TNF)-alpha induced MCP-1 secretion by astrocytes, but not microglia
Leonard et al., Adv Exp Med Biol 1993 : In order of increasing effect, IL-2 + IFN gamma, IL-1 alpha, and LPS caused monocyte secretion of MCP-1
Colotta et al., Am J Pathol 1994 : Induction of MCP-1 transcript by thrombin was not reduced by blocking interleukin-1 and tumor necrosis factor, suggesting that these mediators are not involved in thrombin induced expression of MCP-1
Gruss et al., J Immunol 1996 : Enhancement of fibroblast MCP-1/JE gene expression by IL-2 appeared to result from delayed MCP-1/JE mRNA decay rather than as a consequence of an acceleration of the MCP-1/JE gene transcription rate
Bodine et al., Endocrinology 1996 : Finally, interleukin-1 beta and tumor necrosis factor-alpha ( 1-1000 pM ) stimulated dose dependent increases in the secretion of interleukin-6 and monocyte chemoattractant protein-1 at 34 C and 40C
Elner et al., Invest Ophthalmol Vis Sci 1997 : IL-2 did not induce HRPE IL-8 or MCP-1 , nor did it modulate the effects of the other cytokines