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CSF3 — PTPN11

Text-mined interactions from Literome

Wang et al., Cell Signal 2008 : Mutation of Gab2 Y643 inhibited G-CSF stimulated Erk1/2 activation and Shp2 binding to Gab2
Jack et al., Blood 2009 (MAP Kinase Signaling System) : M-CSF elevates c-Fos and phospho-C/EBPalpha ( S21 ) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification
Zhang et al., Blood 2011 (MAP Kinase Signaling System) : We previously found that G-CSF induces SHP2 tyrosine phosphorylation and that chemical inhibition of SHP1/SHP2 reduces CFU-G and prevents G-CSF but not M-CSF activation of ERK