Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ATP5O
→
MAP2K6
(decreases, ATP5O Activity)
Evidence: to characterize changes in levels of proteins in MKK6 transgenic mouse hearts, focusing on proteins in mitochondria, which play key roles in mediating I/R injury in the heart. Of the 386 mitochondrial proteins identified, the levels of 58 were decreased, while only 2 were increased in the MKK6 transgenic mouse hearts