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IL15 — STAT4

Text-mined interactions from Literome

Chin et al., Nature 2002 (Listeriosis...) : Furthermore, Rip2 deficiency results in impaired interferon-gamma production in both TH1 and natural killer cells, attributed in part to defective interleukin-12 induced Stat4 activation
Strengell et al., J Immunol 2003 : We also show that IL-15 activated the binding of STAT1, STAT3, STAT4 , and STAT5 to the regulatory sites of the IFN-gamma gene
Karpuzoglu et al., Endocrinology 2009 : Signal transducer and activation of transcription ( STAT ) 4beta, a shorter isoform of interleukin-12 induced STAT4 , is preferentially activated by estrogen
Watford et al., J Exp Med 2008 (Toxoplasmosis, Animal) : We investigated the potential roles of Tpl2 in T cells and found that it was induced by interleukin-12 in human and mouse T cells in a Stat4 dependent manner
Thierfelder et al., Nature 1996 : Requirement for Stat4 in interleukin-12 mediated responses of natural killer and T cells
García et al., J Immunol 1998 : Moreover, we showed that this increase in IFN-gamma could be explained by the dual activation of STAT1 and STAT4 by IL-15 and IL-12, respectively