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CREB5 — IL1B
Text-mined interactions from Literome
Wang et al., Prostaglandins Leukot Essent Fatty Acids 1999
:
This was demonstrated by showing that coexpression of
CREB stimulated native but not CRE mutant promoter and that
IL-1beta and PMA
induced less activity with the mutant promoter as compared to the native promoter
Zhao et al., J Neurosci 2004
(Calcium Signaling) :
Using CREB antisense to determine the causal relationship between V1 agonist induced CREB activation and suppression of IL-1beta and TNF-alpha, we demonstrated that decreased
IL-1beta and TNF-alpha gene expression was
dependent on upstream
CREB activation
Srinivasan et al., J Neurosci 2004
:
IL-1beta activates the p38 mitogen activated protein kinase ( MAPK ) signaling pathway and
induces the activation of
CREB in hippocampal neurons, in contrast to the activation of NF-kappaB in hippocampal astrocytes, demonstrating cell type-specific signaling responses to IL-1 in the brain and yielding distinct functional responses