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CD4 — KLRC1
Text-mined interactions from Literome
Groh et al., Nat Immunol 2006
(Carcinoma...) :
In late-stage human tumor settings, we observed MIC-driven proliferation of NKG2D ( + )
CD4 ( + ) T cells that produced the cytokine Fas ligand (FasL) as a
result of
NKG2D costimulation but were themselves protected from Fas mediated growth arrest
Domaica et al., EMBO Rep 2009
(Neoplasms) :
We observed that on co-culture with some melanomas, activated
CD4 ( + ) T cells
promoted degranulation, and
NKG2D- and NKp46 dependent IFN-gamma secretion by NK cells, probably owing to the capture of NKG2D and NKp46 ligands from the tumour-cell surface ( trogocytosis )