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GAD1 — IFNG

Text-mined interactions from Literome

Petrovsky et al., Immunology 2002 (Diabetes Mellitus, Type 1...) : Interleukin-2 (IL-2) basally and IL-2 and interferon-gamma (IFN-gamma) in response to GAD , were detected more frequently and at higher levels in diabetic compared to non-diabetic twins ... OAS activity was increased in diabetic compared to non-diabetic twins and showed a correlation with basal IL-2 and GAD stimulated IFN-gamma and IL-10
Videbaek et al., J Autoimmun 2003 : This clone proliferates and produces IFNgamma in response to GAD ( 65 ) presenting APCs and kills GAD ( 65 ) presenting targets
Li et al., Vaccine 2004 (Autoimmune Diseases...) : Furthermore, data indicated that subcellular localization of GAD had an effect on both the number and function of antigen presenting cells (APCs) recruited by BAX as well as on IFN-gamma secretion, and that diabetes suppression was unlikely to be caused by increased T helper 2 ( Th2 ) -like activity
Diaz et al., Diabetes 1992 (Diabetes Mellitus, Type 1) : They proliferate selectively in the presence of GAD and secrete interleukin 2 and interferon-gamma
Axelsson et al., Cryobiology 2008 (Diabetes Mellitus, Type 1) : Stimulation with GAD ( 65 ) induced higher levels of IL-6, IFN-gamma , TNF-alpha and MIP-1alpha, whereas lower secretion was found for IL-10 and IL-13 in cryopreserved PBMC