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IL15 — IL2RG

Pathways - manually collected, often from reviews:

• KEGG Cytokine-cytokine receptor interaction: IL15 → Complex of IL15RA-IL2RB-IL2RG (protein-protein, activation)
  

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Dip Interaction: IL2RG — IL15 (direct interaction, biochemical) Grabstein et al., Science 1994*
• IRef Dip Interaction: IL2RG — IL15 (direct interaction, fluorescent resonance energy transfer) Damjanovich et al., Proc Natl Acad Sci U S A 1997*
• IRef Dip Interaction: IL2RG — IL15 (direct interaction, cross-linking study) Lehours et al., Eur Cytokine Netw 2000*
• IRef Dip Interaction: IL2RG — IL15 (direct interaction, coimmunoprecipitation) Lehours et al., Eur Cytokine Netw 2000*
• IRef Hprd Interaction: IL2RG — IL15 (in vivo) de Jong et al., J Immunol 1996*
• IRef Innatedb Interaction: Complex of IL2RG-IL2RB-IL15 (unknown, -) Giri et al., EMBO J 1994*
• IRef Ophid Interaction: IL2RG — IL15 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Ginn et al., Hum Mutat 2004 (Genetic Diseases, X-Linked...) : Atypical phenotypes have also been described, but relatively little is known about the mechanisms by which the underlying mutations impair gammac dependent interleukin receptor signalling to produce these disease variants
Adunyah et al., Biochem Biophys Res Commun 1997 : We report that IL-15 induces tyr phosphorylation of the p75IL-2R beta and p64IL-2R gamma subunits and Shc