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PXN — RHO

Text-mined interactions from Literome

Mehta et al., Am J Physiol Cell Physiol 2000 : Role of Rho in Ca ( 2+ ) -insensitive contraction and paxillin tyrosine phosphorylation in smooth muscle ... We investigated whether Rho activation is required for Ca ( 2+ ) -insensitive paxillin phosphorylation, myosin light chain ( MLC ) phosphorylation, and contraction in tracheal muscle ... We conclude that, in tracheal smooth muscle, Rho mediates Ca ( 2+ ) -insensitive contraction and MLC phosphorylation but that Rho is not required for Ca ( 2+ ) -insensitive paxillin tyrosine phosphorylation
Lee et al., J Vasc Surg 2002 : Rho inhibition with 2 microg/mL C3 resulted in the reduction of phosphotyrosine, paxillin , and central microfilament staining
Saito et al., Jpn J Ophthalmol 2004 : Differential regulation of focal adhesion kinase and paxillin phosphorylation by the small GTP binding protein Rho in human corneal epithelial cells
Chen et al., Mol Cell Biol 2005 : Supporting these genetic data, biochemical studies indicate that paxillin regulates Rac and Rho activity, positively regulating Rac and negatively regulating Rho ... Taken together, these data indicate the importance of paxillin modulation of Rho family GTPases during development and identify the LIMK pathway as a critical target of paxillin mediated Rho regulation
Yang et al., American journal of physiology. Renal physiology 2007 : Acid induced tyrosine phosphorylation of the focal adhesion proteins p125(FAK) and paxillin is not Rho kinase dependent
Choi et al., Circ Res 2009 (Chronic Disease...) : We show that mmLDL induced recruitment of spleen tyrosine kinase (Syk) to a TLR4 signaling complex, TLR4 phosphorylation, activation of a Vav1-Ras-Raf-MEK-ERK1/2 signaling cascade, phosphorylation of paxillin , and activation of Rac, Cdc42, and Rho
Needham et al., J Biol Chem 1998 : Galpha12 and Galpha13 stimulate Rho dependent tyrosine phosphorylation of focal adhesion kinase, paxillin , and p130 Crk associated substrate ... We examined whether constitutively active mutants of the Galpha proteins Galpha12 and Galpha13, which together comprise the G12 subfamily of Galpha proteins, induce Rho dependent tyrosine phosphorylation of the focal adhesion proteins p125 focal adhesion kinase, paxillin , and p130 Crk associated substrate
Clark et al., J Cell Biol 1998 : However, subsequent phosphorylation of FAK and paxillin occurs in a Rho dependent manner