Gene interactions and pathways from curated databases and text-mining

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PRKD1 — RELA

Text-mined interactions from Literome

Storz et al., EMBO J 2003 : Protein kinase D mediates a stress induced NF-kappaB activation and survival pathway
Storz et al., Mol Cell Biol 2004 : Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling
Liuwantara et al., Diabetes 2006 : Activation of NF-kappaB by TNF receptor associated factor (TRAF) 2, TRAF6, NF-kappaB inducing kinase, or protein kinase D , which transduce signals downstream of Toll-like receptors, TNF receptors, and free radicals, respectively, were all potent activators of the A20 promoter
Yuan et al., Am J Physiol Gastrointest Liver Physiol 2008 (Pancreatitis) : Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells ... Here, we demonstrate that protein kinase D1 (PKD1) is a key downstream target of PKCdelta and PKCepsilon in pancreatic acinar cells stimulated by two major secretagogues, CCK-8 and the cholinergic agonist carbachol ( CCh ), and that PKD1 is necessary for NF-kappaB activation induced by CCK-8 and CCh