Ashizawa et al., Acta Endocrinol (Copenh) 1989
:
We have already demonstrated the inhibitory effect of interleukin 1 on thyroglobulin gene expression
Resetkova et al., Clin Invest Med 1993
(Graves Disease...) :
We have investigated the in vitro effects of interleukin-1-beta (IL-1-beta), interleukin-2 (IL-2) , tumor necrosis factor-alpha (TNF-alpha), and interferon-gamma (IFN-gamma) on the induction of anti-thyroperoxidase ( anti-TPO ), anti-thyroglobulin ( anti-Tg ), and IgG secreting cells ( SC ) by cultures of pokeweed mitogen ( PWM ) -stimulated peripheral blood mononuclear cells ( PBMC ) obtained from patients with Hashimoto 's thyroiditis ( HT ), Graves ' disease ( GD ), and controls ( C )