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IGFBP1 — PI3

Text-mined interactions from Literome

Mounier et al., Endocrinology 2006 : In subconfluent hepatocytes, insulin inhibition of IGFBP-1 mRNA levels was blocked by inhibiting PI3 kinase activation, and there was a corresponding inhibition of Foxo1/Foxo3 phosphorylation
Finlay et al., J Mol Endocrinol 2006 : In contrast, the activation of PI 3-kinase is required for insulin regulation of IGFBP1 under all conditions tested
Mañes et al., J Biol Chem 1997 : We show that IGFBP-1 inhibits IGF-I induced survival and proliferation of BAF/3 cells, as well as IGF-I mediated activation of phosphatidylinositol 3-kinase (PI 3-K)