Gene interactions and pathways from curated databases and text-mining

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EGFR — GPR33

Text-mined interactions from Literome

Santiskulvong et al., Exp Cell Res 2003 : Matrix metalloproteinases ( MMPs ) have been implicated in the transactivation of the epidermal growth factor receptor (EGFR) induced by G-protein coupled receptor ( GPCR ) agonists
Mifune et al., J Biol Chem 2005 : A G protein coupled receptor agonist, angiotensin II ( AngII ), induces epidermal growth factor (EGF) receptor ( EGFR ) transactivation possibly through metalloprotease dependent, heparin binding EGF (HB-EGF) shedding
Yahata et al., J Biol Chem 2006 : It has been reported that G protein coupled receptor ( GPCR ) activation induces epidermal growth factor (EGF) receptor ( EGFR ) transactivation through the shedding of heparin binding EGF-like growth factor ( HB-EGF )
Fischer et al., Methods Mol Biol 2006 : In this signaling process G protein coupled receptor ( GPCR ) stimulation induces phosphorylation of the EGFR , combining the broad diversity of GPCRs with the potent signaling capacities of this receptor tyrosine kinase
Yin et al., Invest Ophthalmol Vis Sci 2009 : ERK1/2 mediate wounding- and G-protein coupled receptor ligands induced EGFR activation via regulating ADAM17 and HB-EGF shedding
Quinn et al., Mol Endocrinol 2009 (Breast Neoplasms) : Coordinate regulation of estrogen mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein coupled receptor , GPR30
Wang et al., Circ Res 2009 (Carotid Artery Diseases...) : To understand the role of epidermal growth factor receptor (EGFR) transactivation in G protein coupled receptor ( GPCR ) agonist induced signaling events, we have studied the capacity of thrombin in the activation of Gab1-SHP2 in vascular smooth muscle cells ( VSMCs )
Chun et al., Carcinogenesis 2009 (Papilloma...) : G protein coupled receptor ( GPCR ) activation of EGFR has been reported to involve Src 's activation via a GPCR-beta-arrestin-Src complex